Pulse_XP is an innovative, integrated software package designed for the analysis of hormone concentration time-series data for both the basic researcher and clinician. This software package provides tools for the exploration of the aperiodic fluctuations that are typical of serum concentration profiles for many neuroendocrine and peripherally secreted hormones. Included in the suite is the direct pulse detection algorithm, Cluster, as well as several deconvolution algorithms (Pulse, Pulse4, Deconv, and AutoDecon). Additionally, this software package includes an algorithm for Cosinor analysis, as well as the Approximate Entropy, Cross Approximate Entropy and Cross-Correlation algorithms.

We would like to stress that for hormone time-series pulsatility data analysis, based upon extensive simulations, AutoDecon's performance is a substantial improvement over the previous incarnations of the software.

Through funding from the National Institutes of Health, this software has evolved over the past 20 years. The latest incarnation of the software is designed to operate under Windows 2000/XP in a menu-driven, user-friendly format.

While working on updates and improvements, the newest version of the software is available here for download at no charge. User's guides as well as extensive documentation are sure to be valuable assets for any prospective user of this software bundle.